1.    Li S, Wijerathne T, Bhatt A, Jiang W, Lacroix JJ*, Han W*, Luo YL*. A two-step clockwork mechanism opens a proteo-lipidic pore in PIEZO2 channels (under review at Nature Chemical Biology)

2.    Bertaccini GA, Casanellas I, Evans EL, Nourse JL, Dickinson GD, Liu G, Seal S, Ly AT, Holt JR, Wijerathne TD, Yan S, Hui EE, Lacroix JJ, Panicker MM, Upadhyayula S, Parker I, Pathak MM*. Visualizing PIEZO1 Localization and Activity in hiPSC-Derived Single Cells and Organoids with HaloTag Technology. Nature Communications, PMID: 40593468

3.  Lacroix JJ* & Wijerathne TD. Mechanosensitive PIEZO Channels as multimodal mechanotransducers. Biochemical Society Transactions, PMID: 39936392

4.    Lin Y, Lacroix JJ, Sterling JD & Luo YL*. (2024) Dissecting current rectification through asymmetric nanopores. Biophysical Journal, PMID: 39614613
Commented by Kurata, HT and Rowley, CN. (2024) Channel Rectification made simple, PMID: 39863926

5.   Wijerathne TD, Bhatt A, Jiang W, Luo YL* & Lacroix JJ*. (2024) Mammalian PIEZO channels rectify anionic currents. Biophysical Journal, PMID: 39543876
Selected for a Special Issue “Advances in Mechanotransduction, Dedicated to Frederick Sachs”

6.    Wijerathne TD & Lacroix JJ*. (2023) Voltage clamp fluorometry to record flow-activated PIEZO1 currents and fluorometric signals. STAR Protocols, PMID: 38103195

7.    Jiang W, Wijerathne TD, Zhang H, Lin Y, Jo S, Im W, Lacroix JJ* & Luo Y*. (2023) Structural and Thermodynamic Framework for PIEZO1 Modulation by Small Molecules. Proceedings of the National Academy of Sciences U S A, PMID: 38060566
Commented by Li, J. (2023) Biomolecular simulation to elucidate small-molecule modulation of mechanosensor protein, PMID: 38147563

8.    Ozkan AD, Wijerathne TD, Gettas T & Lacroix JJ*. (2023) Force-induced motions of the PIEZO1 blade probed with fluorimetry. Cell Reports, PMID: 37471225

9.    Wijerathne TD*, Ozkan AD & Lacroix JJ*. (2023) Microscopic mechanism of PIEZO1 activation by pressure-induced membrane stretch. Journal of General Physiology, PMID: 36715688
Selected for the Pain Detection and Processing, JGP Collection 2023

10.    Jiang W, Lacroix JJ & Luo LL*. (2022) Importance of Molecular Dynamics Equilibrium Protocol on Protein-lipid Interactions near Channel Pore. Biophysical Reports, PMID: 36425669

11.    Wijerathne WD, Ozkan AD & Lacroix JJ*. (2022) Yoda1's energetic footprint on Piezo1 channels and its modulation by voltage and temperature. Proceedings of the National Academy of Sciences U S A, PMID: 35858335

12.    Yoo S, Mittelstein DR, Hurt RC, Lacroix JJ & Shapiro MG*. (2022) Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification. Nature Communications, PMID: 35078979

13.    Ozkan AD, Gettas T, Sogata A, Phaychanpheng W, Zhou M & Lacroix JJ*. (2021) Mechanical and chemical activation of GPR68 (OGR1) probed with a genetically-encoded fluorescent reporter. Journal of Cell Science, PMID: 34322699
Selected as "Research Highlights" by Journal Editors

14.    Lacroix JJ*. (2021) Dichotomy between heterotypic and homotypic interactions by a common chemical law. Physical Chemistry Chemical Physics, PMID: 34241615
Selected as "2021 HOT PCCP articles"

15.    Jiang W, Del Rosario JS, Botello-Smith W, Zhaoc S, Lin YC, Zhang H, Lacroix JJ*, Rohacs T* & Luo YL*. (2021) Crowding-induced Opening of the Mechanosensitive Piezo1 Channel in Silico. Communications Biology, PMID: 33469156
Selected for a special issue on Mechanobiology

16.    Xie C, Jiang W, Lacroix JJ, Luo Y* & Hao J*. (2020) Insight into Molecular Mechanism for Activin A-Induced Bone Morphogenetic Protein Signaling. International Journal of Molecular Sciences, PMID: 32899497

17.    Botello-Smith W, Zhang H, Ozkan AD, Jiang W, Pham CN, Lacroix JJ* & Luo Y*. (2019) A molecular Mechanism for the Chemical Activation of the Mechanosensitive Piezo1 Channel, Nature Communications, PMID: 31582801

18.    Lacroix JJ* & Ozkan A (2019). Multiplexing Focused Ultrasound Stimulation with Fluorescence Microscopy. Journal of Visualized Experiments, PMID: 30663695

19.    Lacroix JJ*, Botello-Smith WM & Luo Y. (2018) Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1. Nature Communications, PMID: 29795280

20.    Chatterjee P, Botello-Smith WM, Zhang H, Qian L, Alsamarah A, Kent D., Lacroix JJ, Baudry M* & Luo Y*. (2017) Can Relative Binding Free Energy Predict Selectivity of Reversible Covalent Inhibitors? Journal of the American Chemical Society, PMID: 29124934

21.    Botello-Smith WM, Alsamarah A, Chatterjee P, Xie C, Lacroix JJ, Hao J* & Luo Y*. (2017) Polymodal allosteric regulation of Type 1 Serine/Threonine Kinase Receptors via a conserved electrostatic lock. PLoS Computational Biology, PMID: 28827795

Publications as post-doctoral researcher

22.    Brugarolas P, Sánchez-Rodríguez JE, Tsai HM, Basuli F, Cheng SH, Zhang X, Caprariello AV, Lacroix JJ, Freifelder R, Murali D, DeJesus O, Miller RH, Swenson RE, Chen CT, Herscovitch P, Reich DS, Bezanilla F & Popko B* (2018) Development of a PET radioligand for potassium channels to image CNS demyelination. Scientific Reports, PMID: 29330383

23.    Labro AJ, Priest MF, Lacroix JJ, Snyders DJ* & Bezanilla F*. (2015) Kv3.1 uses a timely resurgent K(+) current to secure action potential repolarization. Nature Communications, PMID: 26673941 

24.    Kubota T, Lacroix JJ, Bezanilla F & Correa AM*. (2014) Probing α-310 Transitions in a Voltage-Sensing S4 Helix. Biophysical Journal, PMID: 25185547
Commented by Giraldez, T. (2014) Let’s Twist (the S4) Again, PMID: 25185537

25.    Lacroix JJ, Hyde HC, Campos FV & Bezanilla F*. (2013) Moving Gating Charges through the Gating Pore in a Kv Channel Voltage Sensor. Proceedings of the National Academy of Sciences U S A, PMID: 24782544

26.    Priest MF, Lacroix JJ, Villalba-Galea CA & Bezanilla F*. (2013) S3-S4 Linker length Modulates the Relaxed State of a Voltage-Gated Potassium Channel. Biophysical Journal, PMID: 24268143

27.    Lacroix JJ, Campos FV, Frezza L & Bezanilla F*. (2013) Molecular Bases for the Asynchronous Activation of Sodium and Potassium Channels Required for Nerve Impulses Generation. Neuron, PMID: 23972594
Commented by Braun, A.P. (2013) Built for speed: Molecular properties of the voltage sensor domain underlie the rapid activation of voltage-gated Na+ channels compared with Shaker-type K+ channels, PMID: 24366114
Highlighted in Nature News and Views by Crina Nimigean, 15 August 2022

28.    Labro AJ°, Lacroix JJ°, Villalba-Galea CA, Snyders DJ & Bezanilla F*. (2012) Molecular Mechanism for Depolarization-induced Modulation of Kv Channel Closure. The Journal of General Physiology, PMID: 23071266
Commented by French, R.F. and Finol-Urdaneta, R.K. (2012) Open-state stabilization in Kv channels: Voltage-sensor relaxation and pore propping by a bound ion, PMID: 23071264

29.    Lacroix JJ & Bezanilla F*. (2012). Tuning the voltage sensor motion with a single residue. Biophysical Journal, PMID: 22947880

30.    Allen MJ°, Lacroix JJ°, Ramachandran S, Capone R, Whitlock JL, Ghadge GD, Arnsdorf MF, Roos RP* & Lal R*. (2012). Mutant SOD1 forms ion channel: implications for ALS pathophysiology. Neurobiology of Diseases, PMID: 21930207

31.    Lacroix JJ, Pless SA, Maragliano L, Campos FV, Galpin JD, Ahern CA, Roux B & Bezanilla F*. (2012) Intermediate State Trapping of a Voltage-Sensor. The Journal of General Physiology, PMID: 23183699

32.    Lacroix JJ & Bezanilla F*. (2011). Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor. Proceedings of the National Academy of Sciences U S A, PMID: 21464282

33.    Lacroix JJ, Labro AJ & Bezanilla F*. (2011). Properties of deactivation gating currents in shaker channels. Biophysical Journal, PMID: 21354387
Commented by Shirokov, R. (2011) What's in gating currents? Going beyond the voltage sensor movement, PMID: 21767505

34.    Lacroix J, Halaszovich, CR, Schreiber DN, Leitner MG, Bezanilla F, Oliver D* & Villalba-Galea*, CA (2011). Controlling the activity of PTEN by membrane potential. Journal of Biological Chemistry, PMID: 21454672

Publications as graduate student

35.    Pang V, Counillon L, Lagadic-Gossmann, D, Poet M, Lacroix J, Sergent O, Khan R & Rauch C*. (2012). On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetry. Cell Biochemistry and Biophysics, PMID: 22331497

36.    Tekpli X, Huc L, Lacroix J, Rissel M, Poet M, Noel J, Dimanche-Boitrel MT, Counillon L & Lagadic-Gossmann D*. (2008). Regulation of Na+/H+ exchanger 1 allosteric balance by its localization in cholesterol- and caveolin-rich membrane microdomains. Journal of Cell Physiology, PMID: 18264982

37.    Lacroix J, Poet M, Huc L, Morello V, Djerbi N, Ragno M, Rissel M, Tekpli X, Gounon P, Lagadic-Gossmann D & Counillon L*. (2008). Kinetic analysis of the regulation of the Na+/H+ exchanger NHE-1 by osmotic shocks. Biochemistry, PMID: 19035652

38.    Lacroix J, Poet M, Maehrel C & Counillon L*. (2004) A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens. EMBO reports, PMID: 14710192